Axonal Loss In Normal-Appearing White Matter
In Multiple Sclerosis

  1. Metabolite changes in Normal-Appearing Gray and White Matter are linked with disability in early Primary/Progressive Multiple Sclerosis
    Arch Neurol 2005 Apr;62(4):569-73

  2. Mechanisms of Normal-Appearing Corpus Callosum injury related to PeriCallosal T1 lesions in Multiple Sclerosis using directional Diffusion Tensor and 1H MRS imaging
    J Neurol NeuroSurg Psychiatry 2004 Sep;75(9):1281-6

  3. Disability in Multiple Sclerosis is related to Normal-Appearing Brain Tissue MTR Histogram abnormalities
    Mult Scler 2003 Dec;9(6):566-73

  4. Subpial DeMyelination in the Cerebral Cortex of Multiple Sclerosis patients
    J NeuroPathol Exp Neurol 2003 Jul;62(7):723-32

  5. Assessment of Normal-Appearing White and Gray Matter in Primary Progressive Multiple Sclerosis
    A Diffusion-Tensor MRI study

    Archives of Neurology, Vol. 59 No. 9, September 2002

  6. Measurement of Atrophy in Multiple Sclerosis: pathological basis, methodological aspects and clinical relevance
    Brain 2002 Aug;125(Pt 8):1676-95

  7. White Matter T1 relaxation time Histograms and Cerebral Atrophy in Multiple Sclerosis
    J Neurol Sci 2002 May 15;197(1-2):45-50

  8. Information processing characteristics in subtypes of Multiple Sclerosis
    NeuroPsychologia 2002;40(11):1751-65

  9. Effects of IV MethylPrednisolone on Brain Atrophy in Relapsing/Remitting MS
    Neurology 2001 Oct 9;57(7):1239-47

  10. Correlations of Brain MRI parameters to disability in Multiple Sclerosis
    Acta Neurol Scand 2001 Jul;104(1):24-30

  11. Gray matter T2 HypoIntensity is related to plaques and Atrophy in Multiple Sclerosis Brains
    J Neurol Sci 2001 Mar 15;185(1):19-26

  12. 1H MRSI comparison of White Matter and lesions in Primary/Progressive and Relapsing/Remitting MS
    Mult Scler 2000 Jun;6(3):148-55

  13. Changes in Normal-Appearing Brain Tissue and Cognitive Impairment in Multiple Sclerosis
    J Neurol NeuroSurg Psychiatry 2000 Feb;68(2):157-161

  14. Cortical/SubCortical disease burden and Cognitive Impairment in Multiple Sclerosis
    AJNR Am J NeuroRadiol 2000 Feb;21(2):402-8

  15. HypoIntense lesions on T1 Spin-Echo MRI correlate with disease progression in MS
    Neurology 1996 Dec 47:6 1469-76

  16. InfraTentorial Atrophy on MRI and disability in MS
    Brain 1999 Feb;122 ( Pt 2):291-301

  17. Axonal pathology in Multiple Sclerosis: relationship to Neurologic disability
    Curr Opin Neurol 1999 Jun;12(3):295-302

  1. Axonal loss results in Spinal Cord Atrophy, ElectroPhysiological abnormalities and Neurological deficits following DeMyelination in a Chronic Inflammatory model of Multiple Sclerosis
    Brain 2000 Mar;123 Pt 3:519-31

  2. Quantitative pathological evidence for Axonal loss in Normal-Appearing White Matter in Multiple Sclerosis
    Ann Neurol 2000 Mar;47(3):391-5

  3. Acute Axonal injury in Multiple Sclerosis: Correlation with DeMyelination and Inflammation
    Brain 2000 Jun;123(Pt 6):1174-1183

  4. The PathoGenesis of lesions and Normal-Appearing White Matter changes in Multiple Sclerosis
    Brain 2000 Aug;123(Pt 8):1667-1676

  5. Magnetic Resonance Spectroscopy: imaging Axonal damage in MS
    J NeuroImmunol 1999 Jul 1;98(1):2-6

  6. Relationship between Brain Atrophy and disability: an 8-year follow-up study of Multiple Sclerosis
    Mult Scler 2000 Dec;6(6):373-7

  7. Regional Brain Atrophy is associated with physical disability in Multiple Sclerosis: semiquantitative MRI and relationship to clinical findings
    J NeuroImaging 2001 Apr;11(2):129-36

  8. Axonal loss in Normal-Appearing White Matter in a patient with acute Multiple Sclerosis
    Neurology 2001 Oct 9;57(7):1248-52

  9. Imaging Axonal damage in Multiple Sclerosis by means of MR Spectroscopy
    Neurol Sci 2000;21(4 Suppl 2):S883-7

  10. The contribution of DeMyelination to Axonal Loss in Multiple Sclerosis
    Brain 2006 Jun;129(Pt 6):1507-16

  11. Thalamic Atrophy and Cognition in Multiple Sclerosis
    Neurology 2007 Sep 18;69(12):1213-23

  12. Evolution of different MRI measures in patients with active Relapsing/Remitting Multiple Sclerosis over 2 and 5 years: a case-control study
    J Neurol NeuroSurg Psychiatry 2008 Apr;79(4):407-14